What is the function of riboflavin vitamin b2
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Riboflavin Vitamin B2 (chemical formula: C17H20N4O6, formula quantity 376.37), also known as riboflavin, is slightly soluble in water and is stable when heated in neutral or acidic solutions. It is a component of the prosthetic group of yellow enzymes in the body (yellow enzymes play the role of hydrogen transfer in biological redox). When it is lacking, it will affect the biological oxidation of the body and cause metabolic obstacles. The lesions are mostly manifested as inflammation of the mouth, eyes and external genitalia, such as angular stomatitis, cheilitis, glossitis, conjunctivitis and scrotal inflammation, so this product can be used for the prevention and treatment of the above diseases. The storage of vitamin B2 in the body is very limited, so it must be provided by the diet every day. Two properties of vitamin B2 are the main reasons for its loss: (1) can be destroyed by light; (2) can be destroyed by heating in alkaline solution.
riboflavin vitamin b2 functions：
It is mainly related to the active conjugated double bond existing at the 1,5-position N on isoalloxazine in the vitamin B2 molecule, which can be used as both a hydrogen donor and a hydrogen donor. In the human body, it participates in redox reactions in two forms, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). , such as: succinate dehydrogenase, xanthine oxidase and NADH dehydrogenase, etc.
The main biochemical reactions involved are the production of energy in the respiratory chain, the oxidation of amino acids and lipids, the conversion of purine bases to uric acid, the hydroxylation of aromatic compounds, the synthesis of proteins and certain hormones, the transport, storage and mobilization of iron. Metabolism of polyaldehydes and niacin.
It participates in biological oxidation and energy metabolism in the body, and is related to the metabolism of carbohydrates, proteins, nucleic acids and fats. It can improve the utilization rate of proteins in the body, promote growth and development, and maintain the integrity of skin and cell membranes. It has the function of protecting the skin, hair follicles, mucous membranes and sebaceous glands.
Participating in cell growth and metabolism, it is an essential nutrient for body tissue metabolism and repair, such as strengthening liver function and regulating the secretion of adrenaline.
Participates in the metabolism of vitamin B6 and niacin, and is a model of the coordinated action of B vitamins. As prosthetic groups, FAD and FMN are involved in the conversion of tryptophan to niacin, and the conversion of vitamin B6 to pyridoxal phosphate.
It is related to the absorption, storage and mobilization of iron in the body.
Also has antioxidant activity, possibly related to flavinase-glutathione reductase.
what does vitamin b2 do ?
Promote development and regeneration of cells;
Promote normal growth of skin, nails and hair;
Help prevent and eliminate inflammatory reactions in the mouth, lips, tongue and skin, collectively known as oral reproductive syndrome;
Improve vision and reduce eye fatigue;
Affect the body's absorption of iron;
Combined with other substances, it affects biological oxidation and energy metabolism.
mechanism of action
The main physiological function of vitamin B2 is to promote metabolism as a coenzyme. Riboflavin combines with phosphoric acid and a molecule of protein to become flavinase. This class of enzymes, also known as dehydrogenases, is important in that the very mediated transfer of hydrogen atoms is important for the metabolism of sugars, lipids and amino acids. It is an essential factor for the growth of many animals and microorganisms.
Vitamin B2 binds to specific proteins to produce yellow enzymes. Yellow enzymes play a role in transferring hydrogen in material metabolism and participate in the respiration process of tissues.
lack of symptoms
Insufficient intake and alcoholism lead to a lack of vitamin B2. In addition, some drugs, such as promazine and imipramine for psychosis, anticancer drug doxorubicin, and antimalarial drug Adipin, can inhibit the conversion of vitamin B2 into active coenzyme form, so long-term use of these drugs will cause Deficiency of vitamin B2.
1) Usually mild vitamin B2 deficiency does not have obvious symptoms, but severe vitamin B2 deficiency will cause the following symptoms:
Orogenital Syndrome
Mouth: red lips, milky white corners of the mouth, cracks or even erosion, stomatitis, cheilitis, angular stomatitis, oral mucosal ulcers, glossitis, swelling, pain and map tongue, etc.;
Eyes: blepharitis, photophobia, easy tearing, fatigue, blurred vision, conjunctival hyperemia, hyperplasia of corneal capillaries, causing conjunctivitis, etc.;
Skin: papular or eczematous scrotum (labia in women), nasolabial folds, glabella, eyelid, and retroauricular seborrheic dermatitis;
Scrotal inflammation: the most common, divided into erythematous, papular and eczematous types, especially the erythematous type, which is characterized by symmetrical erythema of the scrotum, clear demarcation, covered with gray-brown scales; papular type is scattered in clusters or fusion of small Papules; eczema type is limited infiltration hypertrophy, lichenification, may have erosion exudate, crusting.
2) Long-term deficiency can lead to growth retardation in children, mild to moderate iron deficiency anemia.
3) Severe deficiency is often accompanied by other B vitamin deficiency symptoms.
Works best with vitamin B6, vitamin C and folic acid. Riboflavin generally does not cause overdose due to its relatively low solubility and limited intestinal absorption.
When the human body lacks B2, there will be problems in the mucosal layer in the human body cavity, causing mucosal lesions and metabolic disorders of mucosal cells. The specific manifestations are mucosal thinning, mucosal damage, and microvascular rupture. The damage caused to the female reproductive organs is even more serious. The most typical symptoms such as vaginal wall dryness, vaginal mucosal congestion, and ulceration directly affect libido, resulting in decreased libido and sexual discomfort. Pathological changes in the internal environment can lead to pain and fear of having sex. Even if you barely live a married life, you will not feel happy. Instead, it will cause the woman to be extremely nervous and panic, aggravating the pain, and it will inevitably affect the harmony of the husband and wife in the long run.
Once the above situation occurs in the married life, it may be caused by the lack of B2 in the woman. The first treatment method is to eat more foods rich in vitamin B2, such as milk and its products, animal liver and kidney, egg yolk, eel, carrot, mushroom, seaweed, celery, orange, tangerine, orange and so on. If the symptoms are serious and not terrible, you can take B2 tablets on time and in moderation, 3 times a day, 10 mg each time (equivalent to 2 tablets), and stop the drug when the symptoms improve.
need crowd
Dietary survey found that vitamin B2 deficiency is more common.
Due to the rapid growth and development of children, the metabolism is strong. If you do not pay attention, children are more likely to lack vitamin B2.
During pregnancy and lactation, women taking birth control pills need more vitamin B2. 1.6 mg during pregnancy, 1.8 mg during lactation, 1.8 mg for the first 6 months, and 1.7 mg for the next 6 months;
People who do not often eat lean meat and dairy products should increase their intake of vitamin B2;
People who are in a state of mental stress for a long time need to supplement the amount of vitamin B2;
People who have been on diet control for a long time due to ulcers or diabetes are more likely to have insufficient vitamin B2 (if people who are suffering from special diseases and are receiving medical treatment, if they want to change the diet prescribed by the doctor, they must consult with the doctor);
The recommended daily intake for adults is 1.3 mg for men and 1.1 mg for women. To prevent riboflavin shortages, care should be taken to protect riboflavin in food. (When eating noodles, one-third to half of the riboflavin goes into the noodle soup)
special effect
Riboflavin is also related to the quality of human sexual life. When the human body lacks riboflavin, especially when it is severely deficient, problems will occur in the mucosal layer of the human body cavity, causing mucosal lesions, loss of libido, and frigidity.
New health benefits of riboflavin:
Diuretic swelling
cancer prevention
Reduce the incidence of cardiovascular and cerebrovascular diseases
Remark:
Vitamin B2 works synergistically with vitamin B6 for the best results.
When ingesting high-calorie foods, you must take in more vitamin B2. It is the natural enemy of vitamin B2 and should be avoided as much as possible.
latest discovery
for the treatment of angina pectoris
People suffering from coronary heart disease, myocardial ischemia and angina pectoris can reduce the frequency of angina pectoris or even disappear after taking 75 mg of vitamin B2 3 times a day for one month. This is because vitamin B2 improves blood supply to the heart.
For the prevention and treatment of migraine
Researchers in Belgium and Luxembourg found that high-dose vitamin B2 supplementation can reduce the frequency and duration of migraine headaches. Migraine headaches are caused by a decrease in the energy reserves of brain cells. And vitamin B2 can increase the potential of mitochondria in brain cells. Therefore, taking vitamin B2 400 mg once a day can effectively treat migraine.
Helps improve the quality of sex life
Studies have shown that the amount of vitamin B2 contained in the human body is closely related to the quality of sexual life. When the human body lacks vitamin B2, the mucosal layer in the cavities of human organs will be damaged, resulting in mucosal thinning, mucosal damage and microvascular rupture. For women, the damage is even more severe. Lack of vitamin B2 in women can be manifested as vaginal dryness, vaginal mucosal congestion, and ulceration, resulting in loss of libido, frigidity and sexual intercourse discomfort. When this happens, vitamin B2 can be taken orally, 10 mg each time, 3 times a day.
cancer prevention
Scientists have found that lack of vitamin B2 can enhance the carcinogenic effect of chemical carcinogens. Therefore, daily supplementation of vitamin B2 can prevent and treat cancer. The usual amount of vitamin B2 supplementation is: 10 mg each time, orally 3 times a day.